The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules

• Main Author: Fiore, Michele (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Chemistry; minerals; n/a; inosine; carbamic acid; prebiotic chemistry; pentopyranose nucleic acid; catalysis; MVC architecture pattern and biological information; carbon dioxide-ammonia ices; stability as a selection pressure; ribozyme and tRNA; translation and the genetic code; AnyLogic software for computer simulation of translation machine; Darwinian evolution; prebiotic information system; genetic code origin; electrochemistry; coevolution of translation machine and the genetic code; digit multiplicity; thermodynamic bottleneck; abasic oligomers; selection; nucleotide stability; AICAR; tRNA-synthetase; hypercycle; nucleotide oligomerization; origin of life; thioester; dry-wet cycles; Chemomimesis; population growth; tRNA and mRNA; diversity; early peptides; Molecular Darwinism; tRNA accretion model; replication; aldol reaction; hydrothermal vents; base pairing; numerical codons; abiogenesis; purine precursor; peptide/RNA world; information; ab initio molecular dynamics; RNA; cysteine; nucleotide and nucleoside synthesis; thiol-rich peptides; novel metalloproteins; transmission; function; energy currency; anharmonicity; arabinopyranose nucleic acid; bridge peptide and aaRS; aminonitriles; mechanochemistry; prebiotic polymerization; origins of life; encoding; carbon fixation; infrared spectra; phosphoryl transfer; metabolism; growth order; layered double hydroxide (LDH) clay; molecular clocks; Monte Carlo; binary patterned amino acid sequences; network expansion simulation; prebiotic soup; nucleotidyltransferases; mixed anhydride; phosphates; translation; ribosome; pentose diphosphate; monosaccharides; systems chemistry; reduction; imidazoles; protein design
• Online Access: DOAB: download the publication; DOAB: description of the publication

Studying the origin of life is one of man's greatest achievements over the last sixty years. The fields of interest encompassed by this quest are multiple and interdisciplinary: chemistry, physics, biology, biochemistry, mathematics, geology but also statistics, atmospheric science, meteorology...