Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation

• Main Author: Florence E. Roufosse (auth)
• Other Authors: Mats W. Johansson (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Medicine; ILC2; Hypereosinophilic Syndrome; mast cell; Th2 cell; Eosinophil Biology; Asthma; Eosinophilic Esophagitis
• Online Access: DOAB: download the publication; DOAB: description of the publication

With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much re...