Pathophysiology of the Basal Ganglia and Movement Disorders: Gaining New Insights from Modeling and Experimentation to Influence the Clinic

• Main Author: Olivier Darbin (auth)
• Other Authors: Daniela Andres (auth), Marcelo Merello (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Neurosciences; Braak's hypothesis; basal ganglia; Parkinson's disease; cycling; movement disorders; computational modeling; Huntington's disease; non-motor symptoms; nonlinear dynamics; deep brain stimulation
• Online Access: DOAB: download the publication; DOAB: description of the publication

The basal ganglia constitute a group of subcortical structures, highly interconnected among themselves, as well as with the cerebral cortex, thalamus and other brain areas. These nuclei play a central role in the control of voluntary movement, and their specific pathology comprises the group of dise...