Personalizing Simulations of the Human Atria : Intracardiac Measurements, Tissue Conductivities, and Cellular Electrophysiology
This work addresses major challenges of heart model personalization. Analysis techniques for clinical intracardiac electrograms determine wave direction and conduction velocity from single beats. Electrophysiological measurements are simulated to validate the models. Uncertainties in tissue conducti...
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Main Author: | |
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Format: | Electronic Book Chapter |
Language: | English |
Published: |
KIT Scientific Publishing
2011
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Series: | Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering
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Subjects: | |
Online Access: | DOAB: download the publication DOAB: description of the publication |
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Summary: | This work addresses major challenges of heart model personalization. Analysis techniques for clinical intracardiac electrograms determine wave direction and conduction velocity from single beats. Electrophysiological measurements are simulated to validate the models. Uncertainties in tissue conductivities impact on simulated ECGs. A minimal model of cardiac myocytes is adapted to the atria. This makes personalized cardiac models a promising technique to improve treatment of atrial arrhythmias. |
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Physical Description: | 1 electronic resource (VI, 152 p. p.) |
ISBN: | KSP/1000022290 9783866446465 |
Access: | Open Access |