Physiology and Pathophysiology of the Extracellular Calcium-Sensing Receptor

• Main Author: Enikö Kallay (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Physiology; proliferation and differentiation; metastasis; vitamin D; G protein-coupled receptor (GPCR); crystal structure; parathyroid hormone (PTH); cancer; Alzheimer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Calcium is vital for human physiology; it mediates multiple signaling cascades, critical for cell survival, differentiation, or death both as first and as second messenger. The role of calcium as first messenger is mediated by the G-protein coupled receptor, the extracellular calcium-sensing recepto...