Programming the HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation

• Main Author: Nikolaos P. Daskalakis (auth)
• Other Authors: Rachel Yehuda (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; HPA axis; Vulnerability; resilience; early life stress; materna
• Online Access: DOAB: download the publication; DOAB: description of the publication

Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later...