Promiscuous functions of the prion protein gene family

• Main Author: Jean-Luc Vilotte (auth)
• Other Authors: Sophie Mouillet-Richard (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Biology, life sciences; Stem Cells; Neuroprotection; Placenta; abeta; Aging; Embryonic and Fetal Development; Cell Adhesion; Gonads; Cell signaling; prion protein
• Online Access: DOAB: download the publication; DOAB: description of the publication

The cellular prion protein PrPC is a ubiquitous GPI-anchored protein. While PrPC has been the focus of intense research for its involvement in a group of neurodegenerative disorders known as transmissible spongiform encephalopathies (TSE), much less attention has been devoted to its physiological fu...