PrPSc Prions: State of the Art

• Main Author: Jesús R. Requena (Ed.) (auth)
• Other Authors: Joaquín Castilla (Ed.) (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2018
• Subjects: Medicine; Prion propagation; Therapy; Scrapie; Chronic wasting disease; Gerstmann-Sträussler-Scheinker disease; GSS; Creutzfeldt-Jakob disease; Bovine spongiform encephalopathy; Prion structure; CWD; BSE; Prions; Therapeutics; Prion diseases; VPSPr; Variably protease-sensitive prionopathy
• Online Access: DOAB: download the publication; DOAB: description of the publication

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of fatal and transmissible neurodegenerative disorders characterized by long incubation periods, misfolded prion protein (PrP) deposition, and usually spongiform vacuolation. These devastating diseases affect many mamma...