Recent advances in γδ T cell biology: New ligands, new functions, and new translational perspectives

• Main Author: Dieter Kabelitz (auth)
• Other Authors: Julie Dechanet-Merville (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; Infection; Butyrophilin 3A1; Tumor-infiltrating lymphocytes; cancer immunotherapy; IL-17; Pyrophosphates
• Online Access: DOAB: download the publication; DOAB: description of the publication

Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional a/ß T-cells, the available number of germline genes coding for T-cell rece...