Regulation of immune system cell functions by protein kinase C

• Main Author: Amnon Altman (auth)
• Other Authors: Noah Isakov (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2014
• Series: Frontiers Research Topics
• Subjects: Medicine; T cell activation; lymphocyte stimulation; cell growth regulation; Protein Kinase C; signal transduction pathways
• Online Access: DOAB: download the publication; DOAB: description of the publication

Members of the protein kinase C (PKC) family of Ser/Thr kinases are encoded by nine distinct but closely related genes, which give rise to more than 12 different protein isoforms via a mechanism of alternative RNA splicing. Most PKC proteins are ubiquitously expressed and participate in a plethora o...