Regulation of immune system cell functions by protein kinase C

• Autor principal: Amnon Altman (auth)
• Outros Autores: Noah Isakov (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: Frontiers Media SA 2014
• Colecção: Frontiers Research Topics
• Assuntos: Medicine; T cell activation; lymphocyte stimulation; cell growth regulation; Protein Kinase C; signal transduction pathways
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

Members of the protein kinase C (PKC) family of Ser/Thr kinases are encoded by nine distinct but closely related genes, which give rise to more than 12 different protein isoforms via a mechanism of alternative RNA splicing. Most PKC proteins are ubiquitously expressed and participate in a plethora o...