Regulation of immune system cell functions by protein kinase C

• Hoofdauteur: Amnon Altman (auth)
• Andere auteurs: Noah Isakov (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2014
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; T cell activation; lymphocyte stimulation; cell growth regulation; Protein Kinase C; signal transduction pathways
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Members of the protein kinase C (PKC) family of Ser/Thr kinases are encoded by nine distinct but closely related genes, which give rise to more than 12 different protein isoforms via a mechanism of alternative RNA splicing. Most PKC proteins are ubiquitously expressed and participate in a plethora o...