Regulation of red cell life-span, erythropoiesis, senescence and clearance

• Main Author: Anna Bogdanova (auth)
• Other Authors: Lars Kaestner (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2014
• Series: Frontiers Research Topics
• Subjects: Physiology; Erythropoiesis; senescence; neocytolysis; blood storage; Clearance; Vesiculation; erythrocyte
• Online Access: DOAB: download the publication; DOAB: description of the publication

Human red blood cells are formed mainly in the bone marrow and are believed to have an average life span of approximately 120 days. However, is it true for all red blood cells? What are the changes associated with red cell maturation, adulthood and senescence? What are the determinants of red cell l...