Ribosome Inactivating Toxins

• Main Author: Daniel Gillet (Ed.) (auth)
• Other Authors: Julien Barbier (Ed.) (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Medicine; toxin; Shiga toxin; ricin; Ribosome inactivating protein
• Online Access: DOAB: download the publication; DOAB: description of the publication

Ribosome inactivating proteins (RIPs) form a vast family of hundreds of toxins from plants, fungi, algae and bacteria. RIP activities have also been detected in animal tissues. They target a single adenine of a ribosomal RNA, thereby blocking protein synthesis and leading intoxicated cells to apopto...