Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function, 2nd Edition

• मुख्य लेखक: Michel Kranendonk (auth)
• अन्य लेखक: Wayne L. Backes (auth), Ulrich M. Zanger (auth), Amit V. Pandey (auth), Colin J. Henderson (auth), Yuji Ishii (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2018
• श्रृंखला: Frontiers Research Topics
• विषय: Pharmacology; POR; Pharmacogenetics; UGT; Biocatalysis; UDP-glucuronosyltransferase; Cytochrome P450; Drug metabolism; Membrane-associated progesterone receptor; PXR; Steroids
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For example, cytochrome P450 proteins, which metabolize a vast array of drugs, st...