Roles of NF-κB in Cancer and Their Therapeutic Approaches

• Main Author: Véronique Baud (Ed.) (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2018
• Subjects: Biology, life sciences; solid tumors hematological malignancies; animal models; biomarkers; cancer targeted therapeutics; oncogenomics; mechanism-based drug development; cancer targeted diagnosis; molecular targets; NF-kB subunit; epigenetics; NF-kB signaling pathways; miRNA; ubiquitin-proteasome pathway; clinical trials; gene expression profiling
• Online Access: DOAB: download the publication; DOAB: description of the publication

Although mortality rates have declined in recent years, the majority of cancers are still difficult to treat and the medical need for better cancer treatment is evident. The current anticancer armamentarium includes many active agents that are applied across tumor types. However, most of these broad...