Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond

Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as risk markers. This strategy has been successful at preventing harmful drugs from being marketed, but criticized for leading to early withdrawal of potentially safe drugs. Here we collected a series of...

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Bibliographic Details
Main Author: Stefano Morotti (auth)
Other Authors: Eleonora Grandi (auth), Esther Pueyo (auth), Blanca Rodriguez (auth)
Format: Electronic Book Chapter
Language:English
Published: Frontiers Media SA 2018
Series:Frontiers Research Topics
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Online Access:DOAB: download the publication
DOAB: description of the publication
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