Schizophrenia: A Consequence of Gene-Environment Interactions?

• Main Author: Jonathon C Arnold (auth)
• Other Authors: Tim Karl (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Neurosciences; environment; gene; GxE; Interaction; two hit hypothesis; Schizophrenia; animal model
• Online Access: DOAB: download the publication; DOAB: description of the publication

Schizophrenia is a multi-factorial disease characterized by a high heritability and environmental risk factors (e.g. stress and cannabis use). In recent years, an increasing number of researchers worldwide have started investigating the 'two-hit hypothesis' of schizophrenia predicting that...