Searching for Immune Tolerance Manipulating New Molecules and Exploiting New Concepts on Lymphocyte Biology

• Auteur principal: Sergio Quezada (auth)
• Autres auteurs: Juan C. Aguillon (auth), Pino-Lagos (auth), Diego Francisco Catalan (auth)
• Format: Électronique Chapitre de livre
• Langue: anglais
• Publié: Frontiers Media SA 2016
• Collection: Frontiers Research Topics
• Sujets: Medicine; Autoimmunity; immuneregulation; Transplantation; tolerance
• Accès en ligne: DOAB: download the publication; DOAB: description of the publication

The break on immune tolerance is a common point between autoimmune diseases and the uncontrolled effector immune responses against allo-antigens in transplantation. Among the past years, several approaches to restore a suppressive immune state have included the targeting of co-stimulatory/inhibitory...