Searching for Immune Tolerance Manipulating New Molecules and Exploiting New Concepts on Lymphocyte Biology

• Main Author: Sergio Quezada (auth)
• Other Authors: Juan C. Aguillon (auth), Pino-Lagos (auth), Diego Francisco Catalan (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; Autoimmunity; immuneregulation; Transplantation; tolerance
• Online Access: DOAB: download the publication; DOAB: description of the publication

The break on immune tolerance is a common point between autoimmune diseases and the uncontrolled effector immune responses against allo-antigens in transplantation. Among the past years, several approaches to restore a suppressive immune state have included the targeting of co-stimulatory/inhibitory...