Self-Eating on Demand: Autophagy in Cancer and Cancer Therapy

• Main Author: Jon D. Lane (auth)
• Other Authors: Patrizia Agostinis (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Medicine; Pancreatic cancer; Therapy; miRNAs; Cell death; Tumor Microenvironment; Anti-tumor immunity; Hypoxia; Autophagy; Cell Division; Cancer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Macroautophagy, the major lysosomal pathway for recycling intracellular components including whole organelles, has emerged as a key process modulating tumorigenesis, tumor-stroma interactions, and cancer therapy. An impressive number of studies over the past decade have unraveled the plastic role of...