Sex Hormone Receptor Signals in Human Malignancies

• Main Author: Miyamoto, Hiroshi (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; FOXA1; COBRA1; n/a; estrogen; progesterone receptor negative; mutational profiling; heterogeneous nuclear ribonucleoprotein K; estrogen receptor alpha; salivary gland tumors; castration-resistant prostate cancer; ELK1; fibroblasts; androgen receptor; melanocytes; drug screening and proteomics; PI3K pathway; NELFB; therapeutic targets; immunohistochemistry; androgen deprivation therapy; ovarian cancer; estrogen receptor; epidermal growth factor receptor; ethinylestradiol; melanoma; breast cancer; keratinocytes; G-protein coupled estrogen receptor; prognosis; levonorgestrel; ultraviolet radiation; sex hormone receptors; upper urinary tract urothelial carcinoma; CRPC; nuclear factor erythroid 2-related factor 2; TP53
• Online Access: DOAB: download the publication; DOAB: description of the publication

Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome m...