Sex Hormone Receptor Signals in Human Malignancies

Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome m...

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Bibliographic Details
Main Author: Miyamoto, Hiroshi (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
Subjects:
Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue "Sex Hormone Receptor Signals in Human Malignancies" coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules. 
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653 |a COBRA1 
653 |a n/a 
653 |a estrogen 
653 |a progesterone receptor negative 
653 |a mutational profiling 
653 |a heterogeneous nuclear ribonucleoprotein K 
653 |a estrogen receptor alpha 
653 |a salivary gland tumors 
653 |a castration-resistant prostate cancer 
653 |a ELK1 
653 |a fibroblasts 
653 |a androgen receptor 
653 |a melanocytes 
653 |a drug screening and proteomics 
653 |a PI3K pathway 
653 |a NELFB 
653 |a therapeutic targets 
653 |a immunohistochemistry 
653 |a androgen deprivation therapy 
653 |a ovarian cancer 
653 |a estrogen receptor 
653 |a epidermal growth factor receptor 
653 |a ethinylestradiol 
653 |a melanoma 
653 |a breast cancer 
653 |a keratinocytes 
653 |a G-protein coupled estrogen receptor 
653 |a prognosis 
653 |a levonorgestrel 
653 |a ultraviolet radiation 
653 |a sex hormone receptors 
653 |a upper urinary tract urothelial carcinoma 
653 |a CRPC 
653 |a nuclear factor erythroid 2-related factor 2 
653 |a TP53 
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