Single-Domain Antibodies: Biology, Engineering and Emerging Applications

• Huvudskapare: Kevin A. Henry (auth)
• Övriga skapare: C. Roger MacKenzie (auth)
• Materialtyp: Elektronisk Bokavsnitt
• Språk: engelska
• Publicerad: Frontiers Media SA 2018
• Serie: Frontiers Research Topics
• Ämnen: Medicine; antibody engineering; antibody discovery; therapeutic antibody; diagnostic antibody; single-domain antibody
• Länkar: DOAB: download the publication; DOAB: description of the publication

Single-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications. SdAbs are naturally produced as the variable domains of the heavy chain-only antibodies of camelid ruminants and cartilaginous fishes, but c...