State-of-the-Art Research on C1q and the Classical Complement Pathway

• Main Author: Christine Gaboriaud (auth)
• Other Authors: Nicole M. Thielens (auth), Uday Kishore (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; C1 complex; classical pathway activation; Autoimmunity; c1q; C1s; emerging functions; gC1q structure; complement
• Online Access: DOAB: download the publication; DOAB: description of the publication

C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of ligands derived from self, non-self and altered self via its hetero...