Tailoring NK Cell Receptor-Ligand Interactions: an Art in Evolution. 2nd Edition

• 第一著者: Gianfranco Pittari (auth)
• その他の著者: Antoine Toubert (auth), Ulrike Koehl (auth)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Frontiers Media SA 2018
• シリーズ: Frontiers Research Topics
• 主題: Medicine; Chimeric antigen receptors; Checkpoint inhibitors; NK receptors; Immunotherapy; Transplantation; Natural killer cells; Immune evasion; Cancer; Bispecific antibodies
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is mediated by positive signals transduced by activating receptors upon engagement of ligands on target surface. These stimulatory pathways are counterbalanced by inhibitory receptors that raise NK cell activ...