Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

• מחבר ראשי: Changjun Yin (auth)
• מחברים אחרים: Andreas J.R. Habenicht (auth), Pasquale Maffia (auth), Sarajo Mohanta (auth)
• פורמט: אלקטרוני Book Chapter
• שפה: אנגלית
• יצא לאור: Frontiers Media SA 2017
• סדרה: Frontiers Research Topics
• נושאים: Medicine; Autoimmunity; nonresolving peripheral tissue inflammation; Autoinflammation; Tertiary lymphoid organs; dichotomies of immune responses; disease immunity; Immune Tolerance; antigen
• גישה מקוונת: DOAB: download the publication; DOAB: description of the publication

The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...