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Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...

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Opis bibliograficzny
1. autor: Changjun Yin (auth)
Kolejni autorzy: Andreas J.R. Habenicht (auth), Pasquale Maffia (auth), Sarajo Mohanta (auth)
Format: Elektroniczne Rozdział
Język:angielski
Wydane: Frontiers Media SA 2017
Seria:Frontiers Research Topics
Hasła przedmiotowe:
Medicine
Autoimmunity
nonresolving peripheral tissue inflammation
Autoinflammation
Tertiary lymphoid organs
dichotomies of immune responses
disease immunity
Immune Tolerance
antigen
Dostęp online:DOAB: download the publication
DOAB: description of the publication
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Opis
Streszczenie:The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
Opis fizyczny:1 electronic resource (235 p.)
ISBN:978-2-88945-180-7
9782889451807
Ograniczenie dostępu:Open Access

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