Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...
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| Format: | Electronic Book Chapter |
| Language: | English |
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Frontiers Media SA
2017
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| Series: | Frontiers Research Topics
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| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 245 | 1 | 0 | |a Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity |
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| 520 | |a The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases. | ||
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| 653 | |a Autoimmunity | ||
| 653 | |a nonresolving peripheral tissue inflammation | ||
| 653 | |a Autoinflammation | ||
| 653 | |a Tertiary lymphoid organs | ||
| 653 | |a dichotomies of immune responses | ||
| 653 | |a disease immunity | ||
| 653 | |a Immune Tolerance | ||
| 653 | |a antigen | ||
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