Thymic stromal alterations and genetic disorders of immune system

The pathogenic mechanisms underlying primary T-cell disorders are mainly related to molecular alterations of genes whose expression is intrinsic to hematopoietic cells. However, since the differentiation process requires a crosstalk among thymocytes and the thymic microenvironment, molecular alterat...

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Bibliographic Details
Main Author: Claudio Pignata (auth)
Other Authors: Ana E. Sousa (auth)
Format: Electronic Book Chapter
Language:English
Published: Frontiers Media SA 2015
Series:Frontiers Research Topics
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