Tox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Toxicants and Drugs

• Главный автор: Menghang Xia (auth)
• Другие авторы: Ruili Huang (auth)
• Формат: Электронный ресурс Глава книги
• Язык: английский
• Опубликовано: Frontiers Media SA 2017
• Серии: Frontiers Research Topics
• Предметы: Environmental economics; stress response; predictive model; QSAR; HTS; nuclear receptor; in vitro assay; Tox21
• Online-ссылка: DOAB: download the publication; DOAB: description of the publication

Tens of thousands of chemicals are released into the environment every day. High-throughput screening (HTS) has offered a more efficient and cost-effective alternative to traditional toxicity tests that can profile these chemicals for potential adverse effects with the aim to prioritize a manageable...