Tox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Toxicants and Drugs

• मुख्य लेखक: Menghang Xia (auth)
• अन्य लेखक: Ruili Huang (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2017
• श्रृंखला: Frontiers Research Topics
• विषय: Environmental economics; stress response; predictive model; QSAR; HTS; nuclear receptor; in vitro assay; Tox21
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Tens of thousands of chemicals are released into the environment every day. High-throughput screening (HTS) has offered a more efficient and cost-effective alternative to traditional toxicity tests that can profile these chemicals for potential adverse effects with the aim to prioritize a manageable...