Tox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Toxicants and Drugs

• Glavni autor: Menghang Xia (auth)
• Daljnji autori: Ruili Huang (auth)
• Format: Elektronički Poglavlje knjige
• Jezik: engleski
• Izdano: Frontiers Media SA 2017
• Serija: Frontiers Research Topics
• Teme: Environmental economics; stress response; predictive model; QSAR; HTS; nuclear receptor; in vitro assay; Tox21
• Online pristup: DOAB: download the publication; DOAB: description of the publication

Tens of thousands of chemicals are released into the environment every day. High-throughput screening (HTS) has offered a more efficient and cost-effective alternative to traditional toxicity tests that can profile these chemicals for potential adverse effects with the aim to prioritize a manageable...