Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts

• Hoofdauteur: Susan M. Huang (Ed.) (auth)
• Andere auteurs: Arpad Szallasi (Ed.) (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2018
• Onderwerpen: Pharmacology; resiniferatoxin; pain; TRPA1; TRPV3; TRPV1; TRP channels; TRPM2; respiratory disorders; permanent analgesia; capsaicin; TRPM7; cancer; TRPM8; diabetes; obesity
• Online toegang: DOAB: download the publication; DOAB: description of the publication

The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a "hot" new field of basic research and launched drug discovery efforts into th...