Transplant Rejection and Tolerance: Advancing the Field through Integration of Computational and Experimental Investigations

• Hoofdauteur: Alan S. Perelson (auth)
• Andere auteurs: Kathryn J. Wood (auth), Giorgio Raimondi (auth), Julia C. Arciero (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2017
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; systems biology; theoretical modeling; transplant immunology; biomarkers; big data and bioinformatics; transplant rejection; transplant tolerance; mechanistic models
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Organ transplantation is a life-saving surgical procedure through which the functionality of a failing organ system can be restored. However, without the life-long administration of immunosuppressive drugs, the recipient's immune system will launch a massive immune attack that will ultimately d...