Type I Interferon in Human Autoimmunity

• Main Author: Timothy B. Niewold (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; Multiple Sclerosis; autoimmune thyroid disease; systemic lupus erythematosus; systemic sclerosis; Interferons; Sjogren's Syndrome
• Online Access: DOAB: download the publication; DOAB: description of the publication

The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease. Type I interferons function as a bridge between the innate and adaptive immune systems, and as such play...