The ventricular-subventricular zone: a source of oligodendrocytes in the adult brain

• Hoofdauteur: Oscar Gonzalez-Perez (auth)
• Andere auteurs: Adan Aguirre (auth), Jose Manuel Garcia-Verdugo (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2014
• Reeks: Frontiers Research Topics
• Onderwerpen: Neurosciences; myelin; oligodendrocyte precursor cell; white matter; demyelinating disease; ventricular-subventricular zone; neural regeneration; oligodendrocyte; axolemma; Neural Stem Cells; oligodendrogenesis; remyelination
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Demyelinating diseases are characterized by an extensive loss of oligodendrocytes and myelin sheaths from axolemma, which commonly result in disability in young adults. To date, there is no effective treatment against these neurological disorders. In the adult brain, there are neural stem cells (NSC...