Viral Replication Complexes: Structures, Functions, Applications and Inhibitors

• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2016
• Subjects: replication; polymerase; translation; assembly; quasi-species; structural biology; fidelity; nucleic acid; virus
• Online Access: DOAB: download the publication; DOAB: description of the publication

Viruses are obligate intracellular parasites that need to co-opt a living cell's machinery for replication. At the heart of the viral replication machinery are the nucleic acid polymerases, which are responsible for efficiently copying the viral genome. This process must often be coordinated wi...