Ways to improve tumor uptake and penetration of drugs into solid tumors

• Main Author: Ronald Berenson (auth)
• Other Authors: Angelo Corti (auth), Fabrizio Marcucci (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2014
• Series: Frontiers Research Topics
• Subjects: Medicine; Resistance; microenvironment; Administration; targeting; Penetration; Drug delivery; Permeability; Junctions; Cancer; Integrins
• Online Access: DOAB: download the publication; DOAB: description of the publication

The main scope of this topic is to give an update on pharmacologic and non-pharmacologic approaches to enhance uptake and penetration of cancer drugs into tumors. Inadequate accumulation of drugs in tumors has emerged over the last decade as one of the main problems underlying therapeutic failure an...