Sarcoidosis and Granulomatosis Diagnosis and Management
Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung...
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| Tác giả khác: | |
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| Định dạng: | Điện tử Chương của sách |
| Ngôn ngữ: | Tiếng Anh |
| Được phát hành: |
IntechOpen
2020
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| Những chủ đề: | |
| Truy cập trực tuyến: | DOAB: download the publication DOAB: description of the publication |
| Các nhãn: |
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| Tóm tắt: | Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis. |
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| Mô tả vật lý: | 1 electronic resource (178 p.) |
| số ISBN: | intechopen.73968 9781839628337 9781838810351 9781839628344 |
| Truy cập: | Open Access |