Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen

Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence po...

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Bibliographic Details
Other Authors: Johansson, Anders (Editor), DiRienzo, Joseph M. (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
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DOAB: description of the publication
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245 1 0 |a Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen 
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520 |a Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by/4.0/ 
546 |a English 
650 7 |a Research & information: general  |2 bicssc 
650 7 |a Biology, life sciences  |2 bicssc 
653 |a Aggregatibacter actinomycetemcomitans 
653 |a cagE 
653 |a virB1 
653 |a virB4 
653 |a genotype 
653 |a virulence 
653 |a mRNA assay 
653 |a quantitative ELISA 
653 |a cell lysis assay 
653 |a leukotoxin 
653 |a JP2 genotype 
653 |a cytolethal distending toxin 
653 |a lipopolysaccharides 
653 |a cytokine binding factors 
653 |a horizontal gene transfer 
653 |a outer membrane vesicles 
653 |a biofilm 
653 |a proteomic 
653 |a adherence 
653 |a endocarditis 
653 |a fimbriae 
653 |a JP2 
653 |a periodontitis 
653 |a taxonomy 
653 |a core and accessory genes 
653 |a average nucleotide identity 
653 |a principal component analysis 
653 |a keratins 
653 |a organotypic gingival mucosa 
653 |a A. actinomycetemcomitans 
653 |a RNA-Seq 
653 |a genomic islands 
653 |a core genes 
653 |a accessory genes 
653 |a stress 
653 |a nutrient limitation 
653 |a differentially expressed genes. 
653 |a lymphocytes 
653 |a apoptosis 
653 |a RTX toxin 
653 |a localized aggressive periodontitis 
653 |a LFA-1 
653 |a leukotoxin (LtxA) 
653 |a endocytosis 
653 |a n/a 
653 |a JP2 clone of Aggregatibacter actinomycetemcomitans 
653 |a JP2 in Caucasian 
653 |a microbiological diagnosis 
653 |a adjunctive antibiotics 
653 |a localized aggressive periodontitis: animal studies: human studies 
653 |a landscape ecology 
653 |a damage/response framework 
653 |a bacteremia 
653 |a horseshoe crab 
653 |a Origanum vulgare 
653 |a essential oil 
653 |a antimicrobial activity 
653 |a minimum inhibitory concentration 
653 |a minimal bactericidal concentration 
653 |a cytotoxicity 
653 |a leukotoxin neutralization 
653 |a inflammasome 
653 |a immune response 
653 |a periodontal disease 
653 |a proteomics 
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