Advance in Gluten-Free Diet

• Other Authors: Paolo, Usai-Satta (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; Biology, life sciences; Food & society; irritable bowel syndrome; celiac disease; nonceliac gluten/wheat sensitivity; gluten-free diet; AIDAI score; amylase trypsin inhibitor; non-celiac wheat sensitivity; CD14 lymphocytes; interleukin-1beta; tumor necrosis factor-α; non coeliac wheat sensitivity; gluten; FODMAPs; functional dyspepsia; Celiac disease; iron deficiency without anemia; dietary iron; iron supplementation; women; refractory celiac disease; remission; nickel allergy; allergic contact mucositis; irritable bowel syndrome (IBS); low-nickel diet; gluten-free products; gluten containing products; food composition database; dietary reference intake; prison diets; irritable bowel disease; FODMAP; low FODMAP diet; gluten free diet; non-celiac gluten wheat sensitivity; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The only effective and safe treatment of celiac disease (CD) is a lifelong, strict exclusion of gluten, the so-called gluten-free diet (GFD). As a consequence, strict adherence to the GFD is highly successful and useful to achieve optimal control of symptoms in celiac patients, although, sometimes, nutritional problems can persist despite a strict exclusion of gluten. However, following a strict GFD is not easy and an updated quality assessment of available products is needed for further improvement in gluten-free product development. Similar to CD, GFD is the common dietary approach in non-celiac gluten/wheat sensitivity (NCGWS). NCGWS is another common gluten-related disorder without the diagnostic features of CD. Increasing interest in the association and interaction between irritable bowel syndrome (IBS), functional dyspepsia, and gluten-related disorders can expand our knowledge and understanding of the management of these disorders. In this respect, GFD is considered a therapeutic option in IBS and functional digestive disorders. New insights into the GFD are an exciting scientific challenge for researchers.