Cocrystal Applications in Drug Delivery

• Other Authors: Erxleben, Andrea (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; nitazoxanide; cocrystals; multicomponent crystals; dissolution behavior; supersaturated formulations; crystallization inhibitors; drug-polymer interactions; nano co-crystals; crystal engineering; polydispersity index; zeta potential; particle size; zidovudine; lamivudine; HIV/AIDS; sonochemistry; imidazole N-oxides; barbituric acid; thiobarbituric acid; pharmaceutical cocrystals; mechanochemistry; solid state NMR; X-ray Diffraction; design of experiments; Quality by Design; cocrystal; compaction; nanoindentation; slip plane; tabletability; surface topology; interparticulate bonding area; interparticulate bonding strength; nefiracetam; solid state; solubility; dissolution rate; stability; formulation; diclofenac sodium; L-proline; salt cocrystal; multicomponent crystal; monohydrate; tetrahydrate; dissolution; itraconazole; terephthalic acid; crystal structure; solid-state; thermal analysis; wettability; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

In 2015, the first pharmaceutical cocrystal was approved by the FDA. Since then, the number of cocrystals on the market and in the development pipeline has been slowly but steadily growing. It is now well established that cocrystals are a versatile new approach to oral drug formulation. This Reprint...