PLGA Based Drug Carrier and Pharmaceutical Applications

• Other Authors: Pereira, Maria Carmo (Editor), Loureiro, Joana (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; PLGA; nanoscaled drug delivery; LED; cancer; serum stability; reactive oxygen species; cellular uptake; terahertz spectroscopy; microspheres; drug delivery; formulation development; molecular mobility; vitamin E; tocopherol; PLA; core-shell nanoparticles; controlled drug release; BMP-2; PLGA nanoparticles; Pluronic F68; oxaliplatin; hydrogel; intra-abdominal anti-adhesion barrier; colorectal cancer; experimental design; fractional factorial design; O6-methylguanine DNA methyltransferase (MGMT) protein; glioblastoma multiforme; smart nanocarriers; folic acid; verteporfin; cisplatin; SKOV-3 cells; CHO-K1 cells; electroporation; theranostic cargo; double emulsion approach; NSAIDs; polymeric film; topical drug delivery; trolamine salicylate; triamcinolone acetonide; microcrystal; PLGA microsphere; local delivery; spray-drying technique; intra-articular injection; joint retention; systemic exposure; gadolinium; drug release; polymeric nanocarrier; sorafenib; theranostic nanoparticles; PLGA-PEG; nanoparticles; platelet; activation; aggregation; binding; uptake; tissue engineering; Huntington's disease; siRNA; microcarriers; mesenchymal stromal cells; drug delivery systems; microfluidics; microparticles; BMP-2-microspheres; hydrogel system; 17-βestradiol release; bone regeneration; osteoporosis; poly-lactide-co-glycolide; polylactic acid; alginate; ophthalmic drug delivery; dexamethasone; PLGA-NPs; nanomedicine; gastrointestinal tract; paclitaxel; in vivo imaging; controlled release; risperidone; microcapsules; oleogels; electron microscopy; three-dimensional X-ray imaging; nano-CT; biodegradable polymers; hydroxy-stearic acid; PLGA nanocapsules; magnetic resonance imaging; photoluminescence; magnetic targeting; multimodal imaging; theranostics; silicon; microsphere; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers used for producing therapeutic devices, such as drug carriers (DC). PLGA is one of the few polymers that the Food and Drug Administration (FDA) has approved for human administration due to its biocompatibility and biodegrada...