Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology

• Autres auteurs: Fioravanti, Antonella (Éditeur intellectuel), Dotta, Francesco (Éditeur intellectuel), Giordano, Antonio (Éditeur intellectuel), Pirtoli, Luigi (Éditeur intellectuel)
• Format: Électronique Chapitre de livre
• Langue: anglais
• Publié: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Sujets: Medicine; miR-27a-5p; acute myocardial infarction; autophagy; apoptosis; hypoxia; MicroRNA (miRNA); miR526b; miR655; oxidative stress; reactive oxygen species (ROS); superoxide (SO); Thioredoxin Reductase 1 (TXNRD1); breast cancer; nucleic acid medicine; pancreatic cancer; clinical trial; siRNA; antisense oligonucleotide; MicroRNA; signal transduction; therapeutic target; miRNAs; ROS; noncoding RNA; microRNA; long noncoding RNA; mitochondrial dysfunction; nitrosative stress. exosome; cross-talk; systemic lupus erythematosus; visfatin; resistin; osteoarthritis; synovial fibroblasts; synovitis; NF-κB; thyroid hormone; liver cancer; metabolism; physiology; ASH; NAFLD; NASH; HCC; HCV; HBV; endometriosis; high-grade serous ovarian cancer; endometriosis-associated ovarian cancer; epithelial-to-mesenchymal transition; chemoresistance; antioxidants; miRNA; cancer; diabetes; beta cells; microRNAs; translation regulation; neurodegeneration; Alzheimer's disease; Parkinson's disease; Huntington's disease; ALS; reactive oxygen species; redox signaling; therapeutic tolerance; therapeutic resistance; n/a
• Accès en ligne: DOAB: download the publication; DOAB: description of the publication

MicroRNAs (miRNAs) are small noncoding RNAs that are 19-24 nucleotides in length, following maturation. Recent evidence has demonstrated their key role as post-transcriptional regulators of gene expression through the binding of specific sequences within target messenger RNA (mRNA). miRNAs are invol...