Pharmacogenomics and Personalized Medicine

• Weitere Verfasser: Cecchin, Erika (Herausgegeben von), Stocco, Gabriele (Herausgegeben von)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Schlagworte: Medicine; CYP2C9; VKORC1; warfarin; warfarin initiation phase of therapy; INR; pharmacogenetics study; pharmacogenomics; pharmacogenetics; genotype; phenotype; alleles; precision medicine; pharmacotranscriptomics; high-throughput analysis; childhood acute lymphoblastic leukemia; clopidogrel; acenocoumarol; CDSS; implementation; azathioprine; inflammatory bowel disease; glutathione-S transferase; pharmacokinetics; nucleoside analogs; microRNAs; gene expression; drug resistance; AML; cisplatin; nephrotoxicity; kidney injury; genetic polymorphisms; pre-emptive; panel; breast cancer subtype; miRNA; pathway; crosstalk network; precision drugs; ovarian cancer; platinum resistance; focal copy number alterations; whole exome sequencing; personalized medicine; human genetics; pharmacology
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient's genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is...