Matrix Metalloproteinase

• Other Authors: Ågren, Magnus S. (Editor), Keller, Ulrich (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; Biology, life sciences; hemagglutinin-B; transwell co-cultures; matrix metalloproteinases; TNF-α; matrix metalloproteinase; peritoneal mesothelial cell; gastric cancer; metastatic dissemination; MT4-MMP; cancer; diseases; aggrecan; aggrecanase; ADAMTS; cartilage; arthritis; MMP-2; MMP-9; inhibitor; allodynia; caspase-3; neuropathic; pain; dorsal root ganglion; spinal nerve ligation; tuberculosis; tuberculous meningitis; HIV-TB-associated IRIS; extracellular matrix breakdown; adult; pediatric; lung; central nervous system; matrix-metalloproteinase; monocytes; inflammation; phagocytosis; apoptosis; blood sampling; anticoagulants; high-molecular-weight heparin; IL-16; sICAM-1; IL-8; T cells; a disintegrin and metalloproteinase; EMMPRIN; CD147; ectodomain shedding; MMPs; PTMs; glycosylation; phosphorylation; glycosaminoglycans; interleukin; IL-6; IL-11; trans-signaling; metalloproteases; ADAM; MMP; meprin; matrix metalloproteinases (MMPs); protease; signaling; invasion; chemokine; cytokine; proteomics; interferon; Agkistrodon venom; metalloproteinase; fibrinogen; antithrombotic; metabolomics; extracellular matrix; cytokines; proteinases; interstitial collagens; wound healing
• Online Access: DOAB: download the publication; DOAB: description of the publication

Zinc-dependent matrix metalloproteinases (MMPs) belong to metzincins that comprise not only 23 human MMPs but also other metalloproteinases, such as 21 human ADAMs (a disintegrin and metalloproteinase domain) and 19 secreted ADAMTSs (a disintegrin and metalloproteinase thrombospondin domain). The ma...