Toxicological Effects of Mycotoxins on Target Cells

• Other Authors: Juan-García, Ana (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; Destruxin A; Bombyx mori; binding protein; BmTudor-sn; Bm12 cell; Ochratoxin A (OTA); human Stem Cells; mycotoxins; cells; cytotoxicity; cell culture; T-2 toxin; HT-2 toxin; apoptosis; autophagy; endophyte; fungi; neurotoxin; lolitrems; ochratoxin A; beauvericin; mixtures; HepG2 cells; genotoxicity; cell cycle; Fusarium; Aspergillus; Penicillium; Alternaria; emerging mycotoxin; in vitro; IPEC-J2; occurrence data; trichothecene; biosynthetic pathway; acetyltransferase; deacetylase; deoxynivalenol; 3-acetyldeoxynivalenol; isotrichodermol; isotrichodermin; differentiated Caco-2 cells; cell apoptosis; transcriptome analysis; hepatocyte; chicken; acute toxicity; combined toxicity; cell protection; silibinin; in silico prediction; co-culture models; mycotoxin interaction; Loewe additivity; combination index; isobologram; Chou-Talalay method; MixLow; IPEC-J2 cells; RNA-seq; inflammation; MAPKs; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results f...