Toxicological Effects of Mycotoxins on Target Cells

Toxicological Effects of Mycotoxins on Target Cells

Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results f...

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Bibliographic Details
Other Authors: Juan-García, Ana (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Medicine
Destruxin A
Bombyx mori
binding protein
BmTudor-sn
Bm12 cell
Ochratoxin A (OTA)
human Stem Cells
mycotoxins
cells
cytotoxicity
cell culture
T-2 toxin
HT-2 toxin
apoptosis
autophagy
endophyte
fungi
neurotoxin
lolitrems
ochratoxin A
beauvericin
mixtures
HepG2 cells
genotoxicity
cell cycle
Fusarium
Aspergillus
Penicillium
Alternaria
emerging mycotoxin
in vitro
IPEC-J2
occurrence data
trichothecene
biosynthetic pathway
acetyltransferase
deacetylase
deoxynivalenol
3-acetyldeoxynivalenol
isotrichodermol
isotrichodermin
differentiated Caco-2 cells
cell apoptosis
transcriptome analysis
hepatocyte
chicken
acute toxicity
combined toxicity
cell protection
silibinin
in silico prediction
co-culture models
mycotoxin interaction
Loewe additivity
combination index
isobologram
Chou-Talalay method
MixLow
IPEC-J2 cells
RNA-seq
inflammation
MAPKs
n/a
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Description
Summary:Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins' effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Physical Description:1 electronic resource (218 p.)
ISBN:books978-3-03936-927-0
9783039369263
9783039369270
Access:Open Access

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