Antitumoral Properties of Natural Products

• Other Authors: Fabiani, Roberto (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; Biology, life sciences; cytotoxic activity; NCI-60 cancer cell line; pristimerin; Salacia crassifolia; Celastraceae; Brazilian Cerrado biome; Salacia elliptica; Cheiloclinium cognatum; Plenckia populnea; Aspergillus fumigatus; Cordyceps sinensis; isochromanes; chiral resolution; ECD calculation; cytotoxicity; coronarin D; JNK; osteosarcoma; Zeylenone; gastric cancer; invasion; migration; apoptosis; anti-cancer agents; anthraquinones; glycosyltransferase; Dendrobium officinale; structure elucidation; anti-tumor activity; plantation mode; AR; Ganoderma tsugae; lipogenesis; prostate cancer; SREBP-1; ursolic acid; betulinic acid; triterpenoids; necrotic; quercetin; quercetagetin; patuletin; lichen; secondary metabolites; tumidulin; stemness potential; colorectal cancer cells; oncogene; transcriptional regulation; neferine; FAK/S6K1; autophagy; human neuroblastoma cells; natural yellow Monascus pigments; water-soluble; antioxidation; MCF-7 cells; phloretin; cell proliferation; inflammation; glucose uptake; Catalpa speciosa; Taxus cuspidata; Magnolia acuminata; phenols; antioxidants; anticancer; Colocasia esculenta; food bioactive; tarin; stable nanocapsules; entrapment efficiency; no-toxicity; preclinical tests; antitumoral activity; chemotherapeutic adjuvant; grape leaves; ASE; TP; Antioxidant activities; Antiproliferative; pro-apoptotic effects; Gene expression; Nutraceuticals; Cucurbitacin B; gefitinib-resistant NSCLC; EGFR; lysosomal degradation; CIP2A; zerumbone; cancer; NF-κB; IL-6/JAK2/STAT3; Akt; FOXO1; multiple myeloma; quality control; naringenin; flavonoids; traditional preparation; cancer stem cells; phytochemicals; plant-derived foods; fruit; vegetable; cell signaling; Artemisia absinthium; endoplasmic reticulum stress; mitochondrial-dependent pathway; melanoma; bee venom; melittin; temozolomide; AKT; MAPK; antrodin C; mTOR; metabolic stability; capsazepine; inflammatory diseases; ROS; TRPV1; PI3K/AKT/mTOR; CLE-10; LC3; MDA-MB-231; lactoferrin hydrolysate; copper; manganese; gastric cancer cells; anti-cancer activity; molecular mechanism; natural product alkaloids; cephalotaxine; protein synthesis inhibition; antiproliferation agents; folk medicine; DLD-1 cells; doxorubicin; chemotherapy; drug resistance; CrataBL; glioblastoma; mesenchymal stem cells; microenvironment; plant lectin; protease inhibitor; cryptolepine; neocryptolepine; isocryptolepine; antiproliferative activity; structure activity relationships; Licochalcone A; ATM-Chk2; 13-ethylberberine; mitochondrial ROS; RT-R breast cancer cells; diallyl disulfide; PI3K/Akt/mTOR pathway; Pulsatilla saponin D; SB365; glioblastoma multiforme; autophagic flux inhibition; lysosomal membrane permeabilization; mitochondrial membrane potential; CLEFMA; p38; proanthocyanins; TNF-α; lung adenocarcinoma; natural compounds; cervical cancer; cell cycle arrest; dicentrine; metastasis; glioma; semi-synthetic derivative; ingenol; Euphorbia tirucalli; protein kinase C; seaweed; porphyran; carrageenan; anti-cancer; natural products; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous disease characterized by the transformation of normal cells into malignant cells, which acquire an uncontrolled growth, immortality, invasiveness, and ability to form distant metastasis. Natural bioactive mole...